Surface functionalization of chitosan as a coating material for orthopaedic applications: A comprehensive review

• Recent progress related to the surface modification of biomedical implant material, i.e. CS-based coatings is reviewed. CS- based result in better cell adhesion, spreading, proliferation and bioactivity etc. Improved mineralisation was achieved by incorporating inorganic particles (eg. CaP, HaP, BG) into CS coatings. Metallic implants have dominated industries for past century load-bearing applications, while polymeric shown great promise tissue engineering applications. The properties such are critical as interaction surfaces, body tissues may lead unfavourable reactions. Desired biocompatibility, corrosion resistance, antibacterial activity. A polymer coating an efficient economical way produce surfaces. lot research has been carried out on chitosan (CS)-modified metallic scaffolds last decade. Different methods electrophoretic deposition, sol-gel methods, dip spin coating, electrospinning, etc . utilized However, a systematic review focussing widely employed techniques lacking. This surveys literature concerning current status orthopaedic applications purpose In this review, various preparation role functionalities determining efficiency discussed. Effect nanoparticle additions interfaces regulating also investigated detail.